TACKLING COMPLEX DISEASES WITH EPISTASIS
نویسندگان
چکیده
منابع مشابه
Why epistasis is important for tackling complex human disease genetics
What is epistasis? The goal of human genetics is to specify the genotypephenotype map; that is, to understand how naturally occurring genetic variants jointly act to modulate disease risk. In a typical genome scan (for example, a genomewide association study), the effect of each variant on the disease trait of interest is interrogated one at a time. The effects of all variants are then summed t...
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ژورنال
عنوان ژورنال: Berkeley Scientific Journal
سال: 2018
ISSN: 2373-8146,1097-0967
DOI: 10.5070/bs3222039581